Les références en gras ont été publiées par les membres de MATHEC
Les références en italique ont pour sujet les cellules stromales mésenchymateuses
2024
EULAR recommendations for the treatment of systemic sclerosis: 2023 update
Del Galdo F, Lescoat A, Conaghan P G, Bertoldo E, Čolić J, Santiago T, Suliman Y A, Matucci-Cerinic M, Gabrielli A, Distler O , Hoffmann-Vold A-M, Castellví I, Balbir-Gurman A, Vonk M, Ananyeva L, Rednic S, Tarasova A, Ostojic P, Boyadzhieva V, El Aoufy K, Farrington S, Galetti I, Denton C P, Kowal-Bielecka O, Mueller-Ladner U, Allanore Y
Ann Rheum Dis. 2024 Oct 17:ard-2024-226430. doi: 10.1136/ard-2024-226430.
Teclistamab-Induced Remission in Refractory Systemic Lupus Erythematosus
Alexander T, Krönke J, Cheng Q, Keller U, Krönke G,
N Engl J Med 2024;391:864-866 Published September 4, 2024 doi: 10.1056/NEJMc240715
Autologous haematopoiesis stem cell transplantation (AHSCT) for treatment-refractory autoimmune diseases in children
Satirer Ö, Henes J C, Döring M, Lesk T, Benseler S, Kuemmerle-Deschner J B
RMD Open 2024;10:e004381. doi: 10.1136/rmdopen-2024-004381
High-dose chemotherapy and autologous hematopoietic stem cell transplantation for progressive systemic sclerosis: a retrospective study of outcome and prognostic factors
Pyka V, Vangala D B, Mika T, Kreuter A, Susok L, Baraliakos X, Treiber H, Schroers R, Nilius-Eliliwi V
Journal of Cancer Research and Clinical Oncology Published: 08 June 2024 Volume 150, article number 301 doi.org/10.1007/s00432-024-05815-1
Distinct Scleroderma Autoantibody Profiles Stratify Patients for Cancer Risk at Scleroderma Onset and During the Disease Course
Kim J S, Woods A, Gutierrez-Alamillo L, Laffoon M, Wigley F M, Hummers L K, Rosen A, Zeger S, Domsic R T, Casciola-Rosen L, Shah A A
Arthritis Rheumatol. 2024 Jan;76(1):68-77. doi: 10.1002/art.42663. Epub 2023 Nov 27.DOI: 10.1002/art.42663
2023
Validity, Reliability, and Differential Item Functioning of English and French Versions of the 10-Item Connor-Davidson Resilience Scale in Systemic Sclerosis: A Scleroderma Patient-Centered Intervention Network Cohort Study
Neyer M A, Henry R S, Carrier M-E, Kwakkenbos L, Wojeck R K, Gietzen A, Gottesman K, Guillot G, Lawrie-Jones A, Mayes M D, Mouthon L, Nielson W R, Richard M, Worron-Sauvé M, Harel D, Malcarne V L, Bartlett S J, Thombs B D, on behalf of the SPIN Investigators
Arthritis Care & ResearchVol. 75, No. 11, November 2023, pp 2369–2378 doi 10.1002/acr.25139
Anti-thymocyte globulin exposure in patients with diffuse cutaneous systemic sclerosis undergoing autologous haematopoietic stem cell transplantation
Chiu Y-H, Drijver A, Admiraal R, Van Rhenen A, Nierkens S, Van Laar J M, Spierings J
J Scleroderma Relat Disord. 2023 Oct; 8(3): 241–246.Published online 2023 Jul 24. doi: 10.1177/23971983231188232
Outcomes in progressive systemic sclerosis treated with autologous hematopoietic stem cell transplantation compared with combination therapy
Keret S, Henig I, Zuckerman T, Kaly L, Shouval A, Awisat A, Rosner I, Rozenbaum M, Boulman N, Dortort Lazar A, Molad Y, Sabbah F, Naffaa M E, Hardak E, Slobodin G, Rimar D
Rheumatology (Oxford). 2023 Sep 6:kead457. doi: 10.1093/rheumatology/kead457.
Differential Item Functioning on the Cochin Hand Function Scale among People with Systemic Sclerosis by Language, Sex, and Disease Subtype: a Scleroderma Patient-centered Intervention Network (SPIN) Cohort Study
Xu M, Harel D, Carrier M-E, Kwakkenbos L, Bartlett S J, Gottesman K, Guillot G, Hummers L, Malcarne V L, Richard M, Thombs B D, on behalf of the SPIN Investigators
Arthritis Care Res (Hoboken). 2023 Jul 24. doi: 10.1002/acr.25199. Online ahead of print.
Regulatory B Cells Contribute to the Clinical Response After Bone Marrow-Derived Mesenchymal Stromal Cell Infusion in Patients With Systemic Sclerosis
Loisel S, Lansiaux P, Rossille D, Ménard C, Dulong J, Monvoisin C, Bescher N, Bézier N, Latour M, Cras A, Farge D, Tarte K
Stem Cells Transl Med. 2023 Apr; 12(4): 194–206.doi: 10.1093/stcltm/szad010
Complete resolution of gastric antral vascular ectasia after autologous haematopoietic stem cell transplantation in systemic sclerosis
Keret S, Zuckerman T,Henig I,Rainis T, Odeh S, Artoul N, Shouval A, Slobodin G, Rimar D
Ann Rheum Dis. 2023 Mar 13;ard-2023-224011. doi: 10.1136/ard-2023-224011.
Differentially expressed genes in systemic sclerosis: Towards predictive medicine with new molecular tools for clinicians
Keret S, Rimar D, Lansiaux P, Feldman E, Lescoat A, Milman N, Farge D, on behalf of MATHEC working group
Autoimmun Rev. 2023 Mar 12;22(6):103314. doi: 10.1016/j.autrev.2023.103314.
Myeloablative autologous haematopoietic stem cell transplantation resets the B cell repertoire to a more naïve state in patients with systemic sclerosis
Adamska J, Zia A, Bloom M.S, Crofford L.J, Furst D.E, Goldmuntz E, Keyes-Elstein L, Mayes M.D, McSweeney P, Nash R.A, Pinckney A, Welch B, Love Z.Z, Sullivan K.M, Robinson W
Ann Rheum Dis. 2023 Mar; 82(3): 357–364. Published online 2022 Oct 14. doi: 10.1136/ard-2021-221925
Mobilization with reduced cyclophosphamide for autologous stem cell transplantation is feasible in patients with systemic sclerosis
Pecher A-C, Ach K R, Vogel W, Henes J C
Rheumatology, Volume 62, Issue SI, February 2023, Pages SI107–SI113, doi.org/10.1093/rheumatology/keac455
Autologous stem cell transplantation improves cardiopulmonary exercise testing outcomes in systemic sclerosis patients
Gadioli A P, Costa-Pereira K, Dias J B E, Moraes D A, Crescêncio J C, Schwartzmann P V, Gallo-Júnior L, Schmidt A, Oliveira M C
Rheumatology, Volume 62, Issue SI, February 2023, Pages SI101–SI106, https://doi.org/10.1093/rheumatology/keac413
Characterising the autoantibody repertoire in systemic sclerosis following myeloablative haematopoietic stem cell transplantation
Ayoglu B, Donato M, Furst D.E, Crofford L.J, Furst D.E, Goldmuntz E, Keyes-Elstein L, James J, Macwana S, Mayes M.D, McSweeney P, Nash R.A, Sullivan K.M, Welch B, Pinckney A Chung L, Khatri P, Utz P.J
Annals of the Rheumatic Diseases Published Online First: 18 January 2023. doi: 10.1136/ard-2021-221926
2022
Hematopoietic Cell Transplantation for Systemic Sclerosis—AReview
Levin D, Osman M S, Durand C, Kim H, Hemmati I, Jamani K, Howlett J G, Johannson K A, Weatherald J, Woo M, Lee J, Storek J
Cells. 2022 Dec 3;11(23):3912. doi: 10.3390/cells11233912.
Reconstitution of the immune system and clinical correlates after stem cell transplantation for systemic sclerosis
Kawashima-Vasconcelos M Y, Santana-Gonçalves M, Zanin-Silva D C, Malmegrim KCR, Oliveira M C
Front Immunol. 2022 Aug 11;13:941011. doi: 10.3389/fimmu.2022.941011.
Mobilization with reduced cyclophosphamide for autologous stem cell transplantation is feasible in patients with systemic sclerosis
Pecher A C, Ach C R, Vogel W, Henes JC
Rheumatology (Oxford). 2022 Aug 11;keac455.doi: 10.1093/rheumatology/keac455.
Safety, immunological effects and clinical response in a phase I trial of umbilical cord mesenchymal stromal cells in patients with treatment refractory SLE
Kamen D L, Wallace C, Li Z, Wyatt M, Paulos C, Wei C, Wang H, Wolf B J, Nietert P J, Gilkeson G
Lupus Sci Med. 2022 Jul;9(1):e000704.doi: 10.1136/lupus-2022-000704.
Stem cell transplantation for systemic sclerosis
Bruera S, Sidanmat H,Molony DA, Mayes M D, Suarez-Almazor M E, Krause K, Lopez-Olivo M A
Cochrane Database Syst Rev. 2022 Jul 29;7(7):CD011819.doi: 10.1002/14651858.CD011819.pub2.
Long-term follow-up after lymphodepleting autologous haematopoietic cell transplantation for treatment-resistant systemic lupus erythematosus
Goklemez S, Hasni S, Hakim F T, Muraro P A, Pirsl F, Rose J, Memon S, Fowler D F, Steinberg S M, Baker E H, Panch S R, Gress R, Illei G G, Lipsky P E, Pavletic S Z
Rheumatology (Oxford). 2022 Aug 3;61(8):3317-3328.doi: 10.1093/rheumatology/keab877.
Non-Classical HLA Determinants of the Clinical Response after Autologous Stem Cell Transplantation for Systemic Sclerosis
Boukouaci W, Lansiaux P, Lambert N C, Picard C, Clave E, Cras A, Marjanovic Z, Farge D, Tamouza R
Int J Mol Sci. 2022 Jun 29;23(13):7223.doi: 10.3390/ijms23137223.
Autologous hematopoietic stem cell transplantation promotes connective tissue remodeling in systemic sclerosis patients
Zanin-Silva D C, Santana-Gonçalves M, Kawashima-Vasconcelos M Y, Lima-Júnior J R, Dias J B E, Moraes D A, Covas D T, Malmegrim K C R, Ramalho L, Oliveira M C
Arthritis Res Ther. 2022 Apr 29;24(1):95.doi: 10.1186/s13075-022-02779-w.
Changes on chest HRCT in systemic sclerosis-related interstitial lung disease after autologous hematopoietic stem cell transplantation
Rheumatology (Oxford)
Pugnet G, Petermann A, Collot S, Otal P, Lansiaux P, Ait Abdallah N, Lorillon G, Resche-Rigon M, Borel C, Marjanovic Z, Farge D , MATHEC-SFGM-TC network
Rheumatology (Oxford). 2022 Jun 10;keac319.doi: 10.1093/rheumatology/keac319.
Apport de la greffe de cellules stromales mésenchymateuses dans la sclérodermie systémique
Lansiaux P, Farge D
Rev Prat. 2022 Apr;72(4):355-362.
Autologous Haematopoietic Stem Cell Transplantation and Systemic Sclerosis: Focus on Interstitial Lung Disease
Bagnato G, Versace A G, La Rosa D, De Gaetano A, Imbalzano E, Chiappalone M, Ioppolo C, Roberts W N, Bitto A, Irrera N, Allegra A, Pioggia G, Gangemi S.
Cells. 2022 Mar; 11(5): 843. Published online 2022 Mar 1. doi: 10.3390/cells11050843
Safety and preliminary efficacy of allogeneic bone marrow-derived multipotent mesenchymal stromal cells for systemic sclerosis: a single-centre, open-label, dose-escalation, proof-of-concept, phase 1/2 study
Farge D, Loisel S, Resche-Rigon M, Lansiaux P, Colmegna I, Langlais D, Charles C, Pugnet G, Maria A, Chatelus E, Martin T, Hachulla E, Kheav D, Lambert N, Wang H, Michonneau D, Martinaud C, Sensebé L, Cras A, Tarte K
Lancet Rheumatol. 2022 Feb;4(2):e91-e104. doi: 10.1016/S2665-9913(21)00326-X. Epub 2022 Jan 5.
2021
Long-term follow-up after lymphodepleting autologous hematopoietic cell transplantation for treatment-resistant systemic lupus erythematosus
Goklemez S, Hasni S, Hakim F T, Muraro P A, Pirsl F, Rose J, Memon S, Fowler D F, Steinberg S M, Baker E H, Panch S R, Gress R, Illei G G, Lipsky P E, Pavletic S Z
Rheumatology (Oxford). 2021 Dec 7;keab877.doi: 10.1093/rheumatology/keab877.
Transplantation of mesenchymal stem cells ameliorates systemic lupus erythematosus and upregulates B10 cells through TGF-β1
Chun W, Tian J, Zhang Y
Stem Cell Res Ther. 2021 Sep 25;12(1):512.doi:10.1186/s13287-021-02586-1.
Life after Autologous Hematopoietic Stem Cell Transplantation for Systemic Sclerosis
Moraes D A, Oliveira M C
J Blood Med. 2021 Nov 9;12:951-964.doi: 10.2147/JBM.S338077. eCollection 2021.
Long term outcomes of the French ASTIS systemic sclerosis cohort using the global rank composite score
Ait Abdallah N, Wang M, Lansiaux P, Puyade M, Berthier S, Terriou L, Charles C, Burt R K, Hudson M, Farge D
Bone Marrow Transplant. 2021 Jun 9.doi: 10.1038/s41409-021-01355-1. Online ahead of print.
Autologous Hematopoietic Stem Cell Transplantation for Behçet’s Disease: A Retrospective Survey of Patients Treated in Europe, on Behalf of the Autoimmune Diseases Working Party of the European Society for Blood and Marrow Transplantation
Puyade M, Patel A, Jer Lim Y, Blank N, Badoglio M, Gualandi F, D Ma D, Maximova N, Greco R, Alexander T, Snowden JA
Front Immunol. 2021 May 6;12:638709.doi: 10.3389/fimmu.2021.638709. eCollection 2021.
Association of Autologous Hematopoietic Stem Cell Transplantation in Systemic Sclerosis With Marked Improvement in Health-Related Quality of Life
Maltez N, Puyade M, Wang M, Lansiaux P, Marjanovic Z, Charles C, Steele R, Baron M, Colmegna I, Hudson M, Farge D, Canadian Scleroderma Research Group and the MATHEC-SFGMTC Network
Arthritis Rheumatol. 2021 Feb;73(2):305-314.doi: 10.1002/art.41519.
Autologous Stem Cell Transplantation In Scleroderma
Farge D, Abdallah NA, Marjanovic Z, Del Papa N.
Presse Med. 2021 Feb 3;104065. doi: 10.1016/j.lpm.2021.104065. Online ahead of print.
Mesenchymal stromal cells for systemic sclerosis treatment
Farge D, Loisel S, Lansiaux P, Tarte K.
Autoimmun Rev. 2021 Mar;20(3):102755. doi:10.1016/j.autrev.2021.102755.
Longitudinal analysis of T-cell receptor repertoires reveals persistence of antigen-driven CD4 + and CD8 + T-cell clusters in systemic sclerosis
Servaas N H, Zaaraoui-Boutahar F, Wichers CGK, Ottria A, Chouri E, Affandi A J, Silva-Cardoso S, van der Kroef M, Carvalheiro T, van Wijk F, Radstake TRDJ, Andeweg A C, Pandit A.
J Autoimmun. 2021 Feb;117:102574. doi: 10.1016/j.jaut.2020.102574
Hematopoietic stem cell transplantation for systemic sclerosis: Brazilian experience
Henrique-Neto Á, Vasconcelos M Y K, Dias J B E, Aparecida de Moraes D, Gonçalves M S, Zanin-Silva D C, Zucoloto T G, De Fátima Cirioli de Oliveira M, Dotoli G M, Weffort L F, Leopoldo V C, Oliveira M C.
Adv Rheumatol . 2021 Feb 6;61(1):9. doi: 10.1186/s42358-021-00166-8.
2020
Acute and Chronic Sarcoid Arthropathies: Characteristics and Treatments From a Retrospective Nationwide French Study
Cacciatore C , Belnou P ,Thietart S, Desthieux C, Versini M, Abisror N, Ottaviani S, Cormier G, Deroux A, Dellal A, Belhomme N, Saidenberg Kermanac’H N, Khafagy P, Michaud M, Lanot S, Carrat F, Fain O and Mékinian A.
AFront Med (Lausanne). 2020; 7: 565420. Published online 2020 Dec 10. doi: 10.3389/fmed.2020.565420
Machine learning predicts stem cell transplant response in severe scleroderma
Franks J M, Martyanov V, Wang Y, Wood T A, Pinckney A, Crofford L J, Keyes-Elstein L, Furst D E, Goldmuntz E, Mayes M D, McSweeney P, Nash R A, Sullivan K M, Whitfield M L
Ann Rheum Dis. 2020 Dec;79(12):1608-1615.doi: 10.1136/annrheumdis-2020-217033. Epub 2020 Sep 15.
Human umbilical cord mesenchymal stem cells ameliorate skin fibrosis development in a mouse model of bleomycin-induced systemic sclerosis
Yang Y, Zhu S, Li Y, Lu Q, Zhang Q, Su L, Zhang Q, Zhao Y, Luo Y, Liu Y
Exp Ther Med. 2020 Dec;20(6):257. doi: 10.3892/etm.2020.9387. Epub 2020 Oct 27.
Autologous hematopoietic stem cell transplantation with reduced-intensity conditioning regimens in refractory Takayasu arteritis: a retrospective multicenter case-series from the Autoimmune Diseases Working Party (ADWP) of the European Society for Blood and Marrow Transplantation (EBMT).
Laurent C, Marjanovic Z, Ricard L, Henes J, Dulery R, Badoglio M, Farge D, Snowden JA, Moraes D, Dias J, Mohty M, Soussan M, Fain O, Arnold R, Alexander T, Oliveira MC, Mekinian A.
Bone Marrow Transplant. 2020 Apr 22. doi: 10.1038/s41409-020-0907-4.
Low B cell counts as risk factor for infectious complications in systemic sclerosis after autologous hematopoietic stem cell transplantation
Gernert M,Tony H-P, Schwaneck EC, Fröhlich M, Schmalzing M.
Arthritis Res Ther. 2020; 22: 183.
Worsening of esophageal dilatation is associated with increase in a high-resolution computed tomography (HRCT) score in early systemic sclerosis-associated interstitial lung disease (SSc-ILD)
Wangkaew S, Losuriya P, Euathrongchit J
Clin Rheumatol. 2020 Aug 15. doi: 10.1007/s10067-020-05346-3.
Pulmonary mucormycosis following autologous hematopoietic stem cell transplantation for rapidly progressive diffuse cutaneous systemic sclerosis
A case report
Boumaza X, Lelièvre L, Guenounou S, Borel C, Huynh A, Beziat G, Delavigne K, Guinault D, Garric M, Piel-Julian M, Paricaud K, Moulis G, Astudillo L, Sailler L, Farge D, Pugnet G
Medicine (Baltimore) 2020 Jul 31; 99(31): e21431. Published online 2020 Jul 31. doi: 10.1097/MD.0000000000021431
Cardiac Safe Hematopoietic Stem Cell Transplantation for Systemic Sclerosis With Poor Cardiac Function: A Pilot Safety Study That Decreases Neutropenic Interval to 5 Days
Burt RK, Han X, Quigley K, Arnautovic I, Shah SJ, Lee DC, Freed BH, Jovanovic B, Helenowski IB
Bone Marrow Transplant. 2020 Jul 1. doi: 10.1038/s41409-020-0978-2.
Autoimmunity and organ damage in systemic lupus erythematosus
Tsokos G C
Nat Immunol. 2020 Jun; 21(6): 605–614. Published online 2020 May 4. doi: 10.1038/s41590-020-0677-6
T cells in SSc skin lesions: knowing your enemy
Fuschiotti P
Nat Rev Rheumatol. 2020 May;16(5):253-254. doi: 10.1038/s41584-020-0404-6.
Predictive Factors for Treatment-Related Mortality and Major Adverse Events After Autologous Haematopoietic Stem Cell Transplantation for Systemic Sclerosis: Results of a Long-Term Follow-Up Multicentre Study
Sandra van Bijnen, Jeska de Vries-Bouwstra, Cornelia H van den Ende, Maaike Boonstra, Lucie Kroft, Bram Geurts, Miranda Snoeren, Anne Schouffoer, Julia Spierings, Jacob M van Laar, Tom Wj Huizinga, Alexandre Voskuyl, Erik Marijt, Walter van der Velden, Frank Hj van den Hoogen, Madelon C Vonk
Ann Rheum Dis. 2020 May 14;annrheumdis-2020-217058. doi: 10.1136/annrheumdis-2020-217058. Online ahead of print.
Health-related quality of life in systemic sclerosis before and after autologous haematopoietic stem cell transplant—a systematic review
Puyade M, Maltez N, Lansiaux P, Pugnet G, Roblot P, Colmegna I, Hudson M, and Farge D
Rheumatology (Oxford). 2020 Apr 1;59(4):779-789. doi:10.1093/rheumatology/kez300.
Autologous Hematological Stem Cell Transplantation for Systemic Sclerosis in Israel.
Rimar D, Butbul Aviel Y, Gefen A, Nevo N, Shen-Orr SS, Starosvetsky E, Rosner I, Rozenbaum M, Kaly L, Boulman N, Slobodin G, Zuckerman T.
Isr Med Assoc J. 2020 Feb;22(2):104-110.
Stem Cell Transplantation for Systemic Sclerosis in Israel: A New Star Is Rising
Farge D
Isr Med Assoc J. 2020 Feb;22(2):116-118.
Efficacy of mesenchymal stem cells in animal models of lupus nephritis: a meta-analysis.
Zhou T, Liao C, Li HY, Lin W, Lin S, Zhong H.
Stem Cell Res Ther. 2020 Feb 4;11(1):48. doi: 10.1186/s13287-019-1538-9.
Autologous stem cell transplantation for progressive systemic sclerosis: a prospective non-interventional study from the European Society for Blood and Marrow Transplantation Autoimmune Disease Working Party.
Henes J, Oliveira MC, Labopin M, Badoglio M, Scherer HU, Del Papa N, Daikeler T, Schmalzing M, Schroers R, Martin T, Pugnet G, Simoes B, Michonneau D, Marijt EWA, Lioure B, Bay JO, Snowden JA, Rovira M, Huynh A, Onida F, Kanz L, Marjanovic Z, Farge D.
Haematologica. 2020 Jan 16. pii: haematol.2019.230128. doi: 10.3324/haematol.2019.230128. [Epub ahead of print]
2019
Current and future perspectives on managementof systemic sclerosis-associated interstitial lung disease
Distler O, Volkmann ER, Hoffmann-Vold AM, Maher TM
Expert Rev Clin Immunol. 2019 Oct;15(10):1009-1017.doi: 10.1080/1744666X.2020.1668269.
Prognostic Factors for Clinical Response in Systemic Lupus Erythematosus Patients Treated by Allogeneic Mesenchymal Stem Cells.
Wen L, Labopin M, Badoglio M, Wang D, Sun L, Farge-Bancel D.
Stem Cells Int. 2019 May 2;2019:7061408. doi: 10.1155/2019/7061408. eCollection 2019.
Ischemic stroke in giant-cell arteritis: French retrospective study
Pariente A, Guédon A, Alamowitch S, Thietart S, Carrat F, Delorme S, Capron J, Cacciatore C, Soussan M, Dellal A, Fain O, Mekinian A
J Autoimmun. 2019 May:99:48-51. doi: 10.1016/j.jaut.2019.01.009. Epub 2019 Feb 5.
Efficacy and Safety of Umbilical Cord Mesenchymal Stem Cell Therapy for Rheumatoid Arthritis Patients: A Prospective Phase I/II Study
Wang L, Huang S, Li S, Li M, Shi J, Bai W, Wang Q, Zheng L, Liu Y.
Drug Des Devel Ther. 2019 Dec 19;13:4331-4340. doi: 10.2147/DDDT.S225613. eCollection 2019.
Current and future perspectives on management of systemic sclerosis-associatedinterstitial lung disease
Distlera O, Volkmannb ER, Hoffmann-Voldc AM, Maher TM
Expert Rev Clin Immunol. 2019 Oct;15(10):1009-1017. doi: 10.1080/1744666X.2020.1668269. Epub 2019 Sep 30.
Automatic Quantitative Computed Tomography Evaluation of the Lungs in Patients With Systemic Sclerosis Treated With Autologous Stem Cell Transplantation.
Wada DT, de Almeida FA, de Moraes DA, Dias JBE, Baddini-Martinez J, Oliveira MC, Koenigkam-Santos M.
J Clin Rheumatol. 2019 Dec 21. doi: 10.1097/RHU.0000000000001242.
Myeloablation followed by autologous stem cell transplantation normalises systemic sclerosis molecular signatures.
Assassi S, Wang X, Chen G, Goldmuntz E, Keyes-Elstein L, Ying J, Wallace PK, Turner J, Zheng WJ, Pascual V, Varga J, Hinchcliff ME, Bellocchi C, McSweeney P, Furst DE, Nash RA, Crofford LJ, Welch B, Pinckney A, Mayes MD, Sullivan KM.
Ann Rheum Dis. 2019 Oct;78(10):1371-1378. doi: 10.1136/annrheumdis-2019-215770.
Global skin gene expression analysis of early diffuse cutaneous systemic sclerosis shows a prominent innate and adaptive inflammatory profile.
Skaug B, Khanna D, Swindell WR, Hinchcliff ME, Frech TM, Steen VD, Hant FN, Gordon JK, Shah AA, Zhu L, Zheng WJ, Browning JL, Barron AMS, Wu M, Visvanathan S, Baum P, Franks JM, Whitfield ML, Shanmugam VK, Domsic RT, Castelino FV, Bernstein EJ, Wareing N, Lyons MA, Ying J, Charles J, Mayes MD, Assassi S.
Ann Rheum Dis. 2019 Nov 25. pii: annrheumdis-2019-215894. doi: 10.1136/annrheumdis-2019-215894.
Adipose-Derived Stem Cells from Systemic Sclerosis Patients Maintain Pro-Angiogenic and Antifibrotic Paracrine Effects In Vitro
Velier M, Simoncini S, Abellan M, Francois P, Eap S, Lagrange A, Bertrand B, Daumas A, Granel B, Delorme B, Dignat George F, Magalon J, Sabatier F.
J Clin Med. 2019 Nov 14;8(11). pii: E1979. doi: 10.3390/jcm8111979.
Mesenchymal stem cell therapy induces FLT3L and CD1c+ dendritic cells in systemic lupus erythematosus patients.
Yuan X, Qin X, Wang D, Zhang Z, Tang X, Gao X, Chen W, Sun L.
Nat Commun. 2019 Jun 7;10(1):2498. doi: 10.1038/s41467-019-10491-8.
Mesenchymal stem cells of Systemic Sclerosis patients, derived from different sources, show a profibrotic microRNA profiling.
Di Benedetto P, Panzera N, Cipriani P, Mastroiaco V, Tessitore A, Liakouli V, Ruscitti P, Berardicurti O, Carubbi F, Guggino G, Bianchi A, Di Marco A, Ciccia F, Alesse E, Giacomelli R.
Sci Rep. 2019 May 9;9(1):7144. doi: 10.1038/s41598-019-43638-0.
Regional grafting of autologous adipose tissue is effective in inducing prompt healing of indolent digital ulcers in patients with systemic sclerosis: results of a monocentric randomized controlled study.
Del Papa N, Di Luca G, Andracco R, Zaccara E, Maglione W, Pignataro F, Minniti A, Vitali C.
Arthritis Res Ther. 2019 Jan 7;21(1):7. doi: 10.1186/s13075-018-1792-8.
Molecular profile and proangiogenic activity of the adipose-derived stromal vascular fraction used as an autologous innovative medicinal product in patients with systemic sclerosis.
Magalon J, Velier M, Simoncini S, François P, Bertrand B, Daumas A, Benyamine A, Boissier R, Arnaud L, Lyonnet L, Fernandez S, Dignat-George F, Casanova D, Guillet B, Granel B, Paul P, Sabatier F.
Ann Rheum Dis. 2019 Jan 5. pii: annrheumdis-2018-214218. doi: 10.1136/annrheumdis-2018-214218
2018
iNOS Activity Is Required for the Therapeutic Effect of Mesenchymal Stem Cells in Experimental Systemic Sclerosis.
Maria ATJ, Rozier P, Fonteneau G, Sutra T, Maumus M, Toupet K, Cristol J P, Jorgensen C, Guilpain P, Noël D.
Front Immunol. 2018 Dec 21;9:3056. doi: 10.3389/fimmu.2018.03056. eCollection 2018. PMID: 30622540
Fibrosis Development in HOCl-Induced Systemic Sclerosis: A Multistage Process Hampered by Mesenchymal Stem Cells.
Maria ATJ, Toupet K, Maumus M, Rozier P, Vozenin M C, Le Quellec A, Jorgensen C, Noël D, Guilpain P.
Front Immunol. 2018 Nov 5;9:2571. doi: 10.3389/fimmu.2018.02571. eCollection 2018. PMID: 30455706
Autologous Hematopoietic Stem Cell Transplantation for Treatment of Systemic Sclerosis.
Del Papa N, Pignataro F, Zaccara E, Maglione W, Minniti A.
Front Immunol. 2018 Oct 16;9:2390
Therapy of scleroderma renal crisis: State of the art
Zanatta E, Polito P, Favaro M, Larosa M, Marson P, Cozzi F, Doria A
Autoimmun Rev. 2018 Sep;17(9):882-889. doi: 10.1016/j.autrev.2018.03.012. Epub 2018 Jul 10.
Sclérodermie systémique : efficacité des immunoglobulines intraveineuses pour l’atteinte cardiaque sévère ?
C. Cacciatore, S. Riviere, A. Cohen, M. Gatfosse, S. Ederhy, O. Fain, A. Mekinian
Rev Med Interne. 2018 Jul;39(7):594-596. doi: 10.1016/j.revmed.2017.12.013. Epub 2018 Feb 4.
Systemic Sclerosis as an Indication for Autologous Hematopoietic Cell Transplantation: Position Statement from the American Society for Blood and Marrow Transplantation.
Sullivan K M, Majhail N S, Bredeson C, Carpenter P A, Chatterjee S, Crofford LJ, Georges GE, Nash R A, Pasquini M C, Sarantopoulos S, Storek J, Savani B, St Clair EW.
Biol Blood Marrow Transplant. 2018 Jun 25. pii: S1083-8791(18)30362-8
Homeostatic proliferation leads to telomere attrition and increased PD-1 expression after autologous hematopoietic SCT for systemic sclerosis.
Arruda LCM, Lima-Júnior J R, Clave E, Moraes DA, Douay C, Fournier I, Moins-Teisserenc H, Covas D T, Simões B P, Farge D, Toubert A, Malmegrim KCR, Oliveira M C.
Bone Marrow Transplant. 2018 Apr 18
Patterns and predictors of skin score change in early diffuse systemic sclerosis from the European Scleroderma Observational Study.
Herrick AL, Peytrignet S, Lunt M, Pan X, Hesselstrand R, Mouthon L, Silman AJ, Dinsdale G, Brown E, Czirják L, Distler JHW, Distler O, Fligelstone K, Gregory WJ, Ochiel R, Vonk MC, Ancuţa C, Ong VH, Farge D, Hudson M, Matucci-Cerinic M, Balbir-Gurman A, Midtvedt , Jobanputra P, Jordan AC, Stevens W, Moinzadeh P, Hall FC, Agard C, Anderson ME, Diot E, Madhok R, Akil M, Buch MH, Chung L, Damjanov NS, Gunawardena H, Lanyon P, Ahmad Y, Chakravarty K, Jacobsen S, MacGregor AJ, McHugh N, Müller-Ladner U, Riemekasten G, Becker M, Roddy J, Carreira PE, Fauchais AL, Hachulla E, Hamilton J, İnanç M, McLaren JS, van Laar JM, Pathare S, Proudman SM, Rudin A, Sahhar J, Coppere B, Serratrice C, Sheeran T, Veale DJ, Grange C, Trad GS, Denton CP.
Ann Rheum Dis. 2018 Apr;77(4):563-570
Systemic sclerosis: Autologous HSCT is efficacious, but can we make it safer?
Burt RK, Farge D.
Nat Rev Rheumatol. 2018 Apr;14(4):189-191.
Factor structure and convergent validity of the Derriford Appearance Scale-24 using standard scoring versus treating ‘not applicable’ responses as missing data: a Scleroderma Patient-centered Intervention Network (SPIN) cohort study.
Merz E L, Kwakkenbos L, Carrier M E, Gholizadeh S, Mills S D, Fox R S, Jewett L R, Williamson H, Harcourt D, Assassi S, Furst D E, Gottesman K, Mayes M D, Moss T P, Thombs B D, Malcarne V L; SPIN Investigators.
BMJ Open. 2018 Mar 6
Validation of the Brief Fear of Negative Evaluation Scale-II in patients with systemic sclerosis: A Scleroderma Patient-centered Intervention Network Cohort study.
Fox RS, Kwakkenbos L, Carrier ME, Mills S D, Gholizadeh S, Jewett L R, Roesch S C, Merz E L, Assassi S, Furst D E, Gottesman K, Mayes M D, Thombs B D, Malcarne V L; SPIN Investigators.
Arthritis Care Res (Hoboken). 2018 Feb 6.
Left Ventricle Replacement Fibrosis Detected by CMR Associated With Cardiovascular Events in Systemic Sclerosis Patients.
Mousseaux E, Agoston-Coldea L, Marjanovic Z, Stanciu R, Deligny C, Perdrix L, Boutouyrie P, Azarine A, Soulat G, Farge D.
J Am Coll Cardiol. 2018 Feb 13;71(6):703-705.
A Long-Term Follow-Up Study of Allogeneic Mesenchymal Stem/Stromal Cell Transplantation in Patients with Drug-Resistant Systemic Lupus Erythematosus.
Wang D, Zhang H, Liang J, Wang H, Hua B, Feng X, Gilkeson GS, Farge D, Shi S, Sun L.
Stem Cell Reports. 2018 Feb 21
Autologous Hematopoietic Stem Cell Transplantation for Systemic Sclerosis: A Systematic Review and Meta-Analysis.
Shouval R, Furie N, Raanani P, Nagler A, Gafter-Gvili A.
Biol Blood Marrow Transplant. 2018 Jan 31.
Immune rebound associates with a favorable clinical response to autologous HSCT in systemic sclerosis patients.
Arruda LCM, Malmegrim KCR, Lima-Júnior J R, Clave E, Dias JBE, Moraes D A, Douay C, Fournier I, Moins-Teisserenc H, Alberdi A J, Covas D T, Simões B P, Lansiaux P, Toubert A, Oliveira M C
Blood Adv. 2018 Jan 23;2(2):126-141
Validation of the Social Appearance Anxiety Scale in Patients with Systemic Sclerosis: A Scleroderma Patient-centered Intervention Network Cohort Study.
Mills SD, Kwakkenbos L, Carrier ME, Gholizadeh S, Fox RS, Jewett LR, Gottesman K, Roesch SC, Thombs BD, Malcarne VL; SPIN Investigators.
Arthritis Care Res (Hoboken). 2018 Jan 17
Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma.
K.M. Sullivan, E.A. Goldmuntz, L. Keyes-Elstein, P.A. McSweeney, A. Pinckney, B. Welch, M.D. Mayes, R.A. Nash, L.J. Crofford, B. Eggleston, S. Castina, L.M. Griffith, J.S. Goldstein, D. Wallace, O. Craciunescu, D. Khanna, R.J. Folz, J. Goldin, E.W. St. Clair, J.R. Seibold, K. Phillips, S. Mineishi, R.W. Simms, K. Ballen, M.H. Wener, G.E. Georges, S. Heimfeld, C. Hosing, S. Forman, S. Kafaja, R.M. Silver, L. Griffing, J. Storek, S. LeClercq, R. Brasington, M.E. Csuka, C. Bredeson, C. Keever-Taylor, R.T. Domsic, M.B. Kahaleh, T. Medsger, and D.E. Furst, for the SCOT Study Investigators*
N Engl J Med. 2018 Jan 4;378(1):35-47.
Mesenchymal stem cell transplantation in systemic lupus erythematous, a mesenchymal stem cell disorder.
Fathollahi A, Gabalou NB, Aslani S.
Lupus. 2018 Jan 1:961203318768889.
2017
Acute and fatal cardiotoxicity following high-dose cyclophosphamide in a patient undergoing autologous stem cell transplantation for systemic sclerosis despite satisfactory cardiopulmonary screening.
Martin M, Fornecker LM, Marcellin L, Mousseaux E, Hij A, Snowden JA, Farge D, Martin T.
Bone Marrow Transplant. 2017 Dec;52(12):1674-1677
Disability, fatigue, pain and their associates in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study.
Peytrignet S, Denton CP, Lunt M, Hesselstrand R, Mouthon L, Silman A, Pan X, Brown E, Czirják L, Distler JHW, Distler O, Fligelstone K, Gregory WJ, Ochiel R, Vonk M, Ancuta C, Ong VH, Farge D, Hudson M, Matucci-Cerinic M, Balbir-Gurman A, Midtvedt Ø, Jordan AC, Stevens W, Moinzadeh P, Hall FC, Agard C, Anderson ME, Diot E, Madhok R, Akil M, Buch MH, Chung L, Damjanov N, Gunawardena H, Lanyon P, Ahmad Y, Chakravarty K, Jacobsen S, MacGregor AJ, McHugh N, Müller-Ladner U, Riemekasten G, Becker M, Roddy J, Carreira PE, Fauchais AL, Hachulla E, Hamilton J, Inanç M, McLaren JS, van Laar JM, Pathare S, Proudman S, Rudin A, Sahhar J, Coppere B, Serratrice C, Sheeran T, Veale DJ, Grange C, Trad GS, Herrick AL
Rheumatology (Oxford). 2017 Nov 30.
Clinical determinants of elevated systolic pulmonary artery pressure measured by transthoracic Doppler echocardiography in early systemic sclerosis.
Carreira PE, Carmona L, Joven BE, Loza E, Andreu JL, Riemekasten G, Vettori S, Allanore Y, Balbir-Gurman A, Airò P, Walker UA, Damjanov N, Ananieva LP, Rednic S, Czirják L, Distler O, Farge D, Hesselstrand R, Corrado A, Caramaschi P, Tikly M, Matucci-Cerinic M; and EUSTAR co-authors.
Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 106(4):114-121
Serum-Mediated Oxidative Stress from Systemic Sclerosis Patients Affects Mesenchymal Stem Cell Function.
Fonteneau G, Bony C, Goulabchand R, Maria ATJ, Le Quellec A, Rivière S, Jorgensen C, Guilpain P, Noël D.
Front Immunol. 2017 Sep 1;8:988
Long-term safety of umbilical cord mesenchymal stem cells transplantation for systemic lupus erythematosus: a 6-year follow-up study.
Wang D, Niu L, Feng X, Yuan X, Zhao S, Zhang H, Liang J, Zhao C, Wang H, Hua B, Sun L.
Clin Exp Med. 2017 Aug;17(3):333-340
Mapping and predicting mortality from systemic sclerosis
Carina Mihai, Gabriella Szücs, Ulrich A Walker, Nicolas Hunzelmann, Duska Martinovic, Vanessa Smith, Carolina de Souza Müller, Carlo Maurizio Montecucco, Daniela Opris, Francesca Ingegnoli, Panayiotis G Vlachoyiannopoulos, Bojana Stamenkovic, Edoardo Rosato, Stefan Heitmann, Jörg H W Distler, Thierry Zenone, Matthias Seidel, Alessandra Vacca, Ellen De Langhe, Srdan Novak, Maurizio Cutolo, Luc Mouthon, Jörg Henes, Carlo Chizzolini, Carlos Alberto von Mühlen, Kamal Solanki, Simona Rednic, Lisa Stamp, Branimir Anic, Vera Ortiz Santamaria, Maria De Santis, Sule Yavuz, Walter Alberto Sifuentes-Giraldo, Emmanuel Chatelus, Jiri Stork, Jacob van Laar, Esthela Loyo, Paloma García de la Peña Lefebvre, Kilian Eyerich, Vanesa Cosentino, Juan Jose Alegre-Sancho, Otylia Kowal-Bielecka, Grégoire Rey, Marco Matucci-Cerinic, Yannick Allanore, on behalf of EUSTAR group.
Ann Rheum Dis. 2017 Aug 23. pii: annrheumdis-2017-211448
Sustained benefit from combined plasmapheresis and allogeneic mesenchymal stem cells transplantation therapy in systemic sclerosis.
Zhang H, Liang J, Tang X, Wang D, Feng X, Wang F, Hua B, Wang H, Sun L.
Arthritis Res Ther. 2017 Jul 19;19(1):165
Treatment outcome in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study (ESOS).
Herrick AL, Pan X, Peytrignet S, Lunt M, Hesselstrand R, Mouthon L, Silman A, Brown E, Czirják L, Distler JHW, Distler O, Fligelstone K, Gregory WJ, Ochiel R, Vonk M, Ancuţa C, Ong VH, Farge D, Hudson M, Matucci-Cerinic M, Balbir-Gurman A, Midtvedt , Jordan AC, Jobanputra P, Stevens W, Moinzadeh P, Hall FC, Agard C, Anderson ME, Diot E, Madhok R, Akil M, Buch MH, Chung L, Damjanov N, Gunawardena H, Lanyon P, Ahmad Y, Chakravarty K, Jacobsen S, MacGregor AJ, McHugh N, Müller-Ladner U, Riemekasten G, Becker M, Roddy J, Carreira PE, Fauchais AL, Hachulla E, Hamilton J, İnanç M, McLaren JS, van Laar JM, Pathare S, Proudman S, Rudin A, Sahhar J, Coppere B, Serratrice C, Sheeran T, Veale DJ, Grange C, Trad GS, Denton CP.
Ann Rheum Dis. 2017 Jul;76(7):1207-1218
International and multidisciplinary expert recommendations for the use of biologics in systemic lupus erythematosus.
Kleinmann JF, Tubach F, Le Guern V, Mathian A, Richez C, Saadoun D, Sacre K, Sellam J, Seror R, Amoura Z, Andres E, Audia S, Bader-Meunier B, Blaison G, Bonnotte B, Cacoub P, Caillard S, Chiche L, Chosidow O, Costedoat-Chalumeau N, Daien C, Daugas E, Derdèche N, Doria A, Fain O, Fakhouri F, Farge D, Gabay C, Guillo S, Hachulla E, Hajjaj-Hassouni N, Hamidou M, Houssiau FA, Jourde-Chiche N, Koné-Paut I, Ladjouz-Rezig A, Lambotte O, Lipsker D, Mariette X, Martin-Silva N, Martin T, Maurier F, Meckenstock R, Mékinian A, Meyer O, Mohamed S, Morel J, Moulin B, Mulleman D, Papo T, Poindron V, Puéchal X, Punzi L, Quartier P, Sailler L, Smail A, Soubrier M, Sparsa A, Tazi-Mezalek Z, Zakraoui L, Zuily S, Sibilia J, Gottenberg JE.
Autoimmun Rev. 2017 Jun;16(6):650-657.
Thymic findings before and after autologous stem cell transplantation for severe systemic sclerosis: a retrospective study using computed tomography in the pre- and post-transplantation setting.
Henes JC, Wirths S, Vogel W, Xenitidis T, Kanz L, Horger M
Clin Exp Rheumatol. 2017 May-Jun;35 Suppl 104(2):11-12
Autologous haematopoietic stem cell transplantation for systemic lupus erythematosus: time ready for a paradigm shift?
Alexander T, Hiepe F
Clin Exp Rheumatol. 2017 May-Jun;35(3):359-361.
Cardiopulmonary assessment of patients with systemic sclerosis for hematopoietic stem cell transplantation: recommendations from the European Society for Blood and Marrow Transplantation Autoimmune Diseases Working Party and collaborating partners.
Farge D, Burt RK, Oliveira MC, Mousseaux E, Rovira M, Marjanovic Z, de Vries-Bouwstra J, Del Papa N, Saccardi R, Shah SJ, Lee DC, Denton C, Alexander T, Kiely DG, Snowden JA; EBMT ADWP Scleroderma Working Group.
Bone Marrow Transplant. 2017 May 22. doi: 10.1038/bmt.2017.56.
Analysis of anti-topoisomerase I antibodies in patients with systemic sclerosis before and after autologous stem cell transplantation.
Henes J, Glaeser L, Kötter I, Vogel W, Kanz L, Klein R.
Rheumatology (Oxford). 2017 Mar 1;56(3):451-456.
Good outcome of severe lupus patients with high-dose immunosuppressive therapy and autologous peripheral blood stem cell transplantation: a 10-year follow-up study.
Leng XM, Jiang Y, Zhou DB, Tian XP, Li TS, Wang SJ, Zhao YQ, Shen T, Zeng XF, Zhang FC, Tang FL, Dong Y, Zhao Y.
Clin Exp Rheumatol. 2017 May-Jun;35(3):494-499
Autologous peripheral blood haematopoietic stem cell transplantation for systemic lupus erythematosus: the observation of long-term outcomes in a Chinese centre.
Cao C, Wang M, Sun J, Peng X, Liu Q, Huang L, Chai Y, Lai K, Chen P, Liu Q, Li Q, Peng Y, Xiong H, Zhang J, Chen M, Zeng K.
Clin Exp Rheumatol. 2017 May-Jun;35(3):500-507
Long-term immune reconstitution and T cell repertoire analysis after autologous hematopoietic stem cell transplantation in systemic sclerosis patients.
Farge D, Arruda LC, Brigant F, Clave E, Douay C, Marjanovic Z, Deligny C, Maki G, Gluckman E, Toubert A, Moins-Teisserenc H.
J Hematol Oncol. 2017 Jan 19;10(1):21. doi: 10.1186/s13045-016-0388-5.
2016
Update of EULAR recommendations for the treatment of systemic sclerosis.
Otylia Kowal-Bielecka, Jaap Fransen, Jerome Avouac, Mike Becker, Agnieszka Kulak, Yannick Allanore, Oliver Distler, Philip Clements, Maurizio Cutolo, Laszlo Czirjak, Nemanja Damjanov, Francesco del Galdo, Christopher P Denton, Jörg H W Distler, Ivan Foeldvari, Kim Figelstone, Marc Frerix, Daniel E Furst, Serena Guiducci, Nicolas Hunzelmann, Dinesh Khanna, Marco Matucci-Cerinic, Ariane L Herrick, Frank van den Hoogen, Jacob M van Laar, Gabriela Riemekasten, Richard Silver, Vanessa Smith, Alberto Sulli, Ingo Tarner, Alan Tyndall, Joep Welling, Frederic Wigley, Gabriele Valentini, Ulrich A Walker, Francesco Zulian, Ulf Müller-Ladner, EUSTAR Coauthors.
Anti-Ephrin Type-B Receptor 2 (EphB2) and Anti-Three Prime Histone mRNA EXonuclease 1 (THEX1) Autoantibodies in Scleroderma and Lupus. 1 (THEX1) Autoantibodies in Scleroderma and Lupus.
Ann Rheum Dis. 2016 Nov 9. pii: annrheumdis-2016-209909editorsnote. doi: 10.1136/annrheumdis-2016-209909.
Quantitative chest CT analysis in patients with systemic sclerosis before and after autologous stem cell transplantation: comparison of results with those of pulmonary function tests and clinical tests.
Kloth C, Maximilian Thaiss W, Preibsch H, Mark K, Kötter I, Hetzel J, Nikolaou K, Henes J, Horger M.
Rheumatology (Oxford). 2016 Oct;55(10):1763-70.
Anti-Ephrin Type-B Receptor 2 (EphB2) and Anti-Three Prime Histone mRNA EXonuclease 1 (THEX1) Autoantibodies in Scleroderma and Lupus. 1 (THEX1) Autoantibodies in Scleroderma and Lupus.
Azzouz DF, Martin GV, Arnoux F, Balandraud N, Martin T, Dubucquoi S, Hachulla E, Farge-Bancel D, Tiev K, Cabane J, Bardin N, Chiche L, Martin M, Caillet EC, Kanaan SB, Harlé JR, Granel B, Diot E, Roudier J, Auger I, Lambert NC.
PLoS One. 2016 Sep 12;11(9):e0160283. doi: 10.1371/journal.pone.0160283.
Evolution of serum cytokine profile after hematopoietic stem cell transplantation in systemic sclerosis patients.
Michel L, Farge D, Baraut J, Marjanovic Z, Jean-Louis F, Porcher R, Grigore EI, Deligny C, Romijn F, Arruda LC, van Pelt J, Levarht N, Verrecchia F, van Laar JM.
Bone Marrow Transplant. 2016 Aug;51(8):1146-9. doi: 10.1038/bmt.2016.77.
Can positron emission tomography be useful to manage systemic sclerosis cardiac involvement?
Redureau E, Lairez O, Hitzel A, Pugnet G.
J Nucl Cardiol. 2016 Aug 26.
Autologous hematopoietic stem cell transplantation has better outcomes than conventional therapies in patients with rapidly progressive systemic sclerosis
Del Papa N, Onida F, Zaccara E, Saporiti G, Maglione W, Tagliaferri E, Andracco R, Vincenti D, Montemurro T, Mircoli L, Vitali C, Cortelezzi A.
Bone Marrow Transplantation (2017) 52, 53–58; doi:10.1038/bmt.2016.211; published online 22 August 2016
Human adipose mesenchymal stem cells as potent anti-fibrosis therapy for systemic sclerosis.
Maria AT, Toupet K, Maumus M, Fonteneau G, Le Quellec A, Jorgensen C, Guilpain P, Noël D.
J Autoimmun. 2016 Jun;70:31-9
Does ex vivo CD34+ positive selection influence outcome after autologous hematopoietic stem cell transplantation in systemic sclerosis patients?
Oliveira MC, Labopin M, Henes J, Moore J, Papa ND, Cras A, Sakellari I, Schroers R, Scherer HU, Cuneo A, Kyrcz-Krzemien S, Daikeler T, Alexander T, Finke J, Badoglio M, Simões B, Snowden JA, Farge D.
Bone Marrow Transplant. 2016 Jun.
Efficacy of sildenafil on ischaemic digital ulcer healing in systemic sclerosis: the placebo-controlled SEDUCE study.
Hachulla E, Hatron PY, Carpentier P, Agard C, Chatelus E, Jego P, Mouthon L, Queyrel V, Fauchais AL, Michon-Pasturel U, Jaussaud R, Mathian A, Granel B, Diot E, Farge-Bancel D, Mekinian A, Avouac J, Desmurs-Clavel H, Clerson P; SEDUCE study group.
Ann Rheum Dis. 2016 Jun;75(6):1009-15. doi: 10.1136/annrheumdis-2014-207001.
Prevention of infections in adults and adolescents with systemic lupus erythematosus: Guidelines for the clinical practice based on the literature and expert opinion.
Mathian A, Arnaud L, Adoue D, Agard C, Bader-Meunier B, Baudouin V, Belizna C, Bonnotte B, Boumedine F, Chaib A, Chauchard M, Chiche L, Daugas E, Ghali A, Gobert P, Gondran G, Guettrot-Imbert G, Hachulla E, Hamidou M, Haroche J, Hervier B, Hummel A, Jourde-Chiche N, Korganow AS, Kwon T, Le Guern V, Le Quellec A, Limal N, Magy-Bertrand N, Marianetti-Guingel P, Martin T, Martin Silva N, Meyer O, Miyara M, Morell-Dubois S, Ninet J, Pennaforte JL, Polomat K, Pourrat J, Queyrel V, Raymond I, Remy P, Sacre K, Sibilia J, Viallard JF, Viau Brabant A, Hanslik T, Amoura Z; le groupe France lupus érythémateux systémique réseau (FLEUR) et les centres de référence et de compétence des lupus et syndromes des antiphospholipides.
Rev Med Interne. 2016 May;37(5):307-20. doi: 10.1016/j.revmed.2016.01.005.
Antifibrotic, Antioxidant, and Immunomodulatory Effects of Mesenchymal Stem Cells in HOCl-Induced Systemic Sclerosis.
Maria AT, Toupet K, Bony C, Pirot N, Vozenin MC, Petit B, Roger P, Batteux F, Le Quellec A, Jorgensen C, Noël D, Guilpain P.
Arthritis Rheumatol. 2016 Apr;68(4):1013-25
Glutathione S Transferases Polymorphisms Are Independent Prognostic Factors in Lupus Nephritis Treated with Cyclophosphamide.
Audemard-Verger A, Martin Silva N, Verstuyft C, Costedoat-Chalumeau N, Hummel A, Le Guern V, Sacré K, Meyer O, Daugas E, Goujard C, Sultan A, Lobbedez T, Galicier L, Pourrat J, Le Hello C, Godin M, Morello R, Lambert M, Hachulla E, Vanhille P, Queffeulou G, Potier J, Dion JJ, Bataille P, Chauveau D, Moulis G, Farge-Bancel D, Duhaut P, Saint-Marcoux B, Deroux A, Manuzak J, Francès C, Aumaitre O, Bezanahary H, Becquemont L, Bienvenu B.
PLoS One. 2016 Mar 22;11(3):e0151696. doi: 10.1371/journal.pone.0151696.
State of the art. Autologous fat graft and adipose tissue-derived stromal vascular fraction injection for hand therapy in systemic sclerosis patients.
Guillaume-Jugnot P, Daumas A, Magalon J, Sautereau N, Veran J, Magalon G, Sabatier F, Granel B.
Curr Res Transl Med. 2016 Jan-Mar;64(1):35-42
2015
Update on mesenchymal stem cell-based therapy in lupus and scleroderma.
Cras A, Farge D, Carmoi T, Lataillade JJ, Wang DD, Sun L.
Arthritis Res Ther. 2015 Nov 3;17:301. doi: 10.1186/s13075-015-0819-7.
Autologous hematopoietic stem cell transplantation reverses skin fibrosis but does not change skin vessel density in patients with systemic sclerosis.
Daikeler T, Kump E, Stern M, Hügle T, Hij A, Haeuserman P, Farge D.
Pathol Biol (Paris). 2015 Sep;63(4-5):164-8
Transforming growth factor-β increases interleukin-13 synthesis via GATA-3 transcription factor in T-lymphocytes from patients with systemic sclerosis.
Baraut J, Farge D, Jean-Louis F, Masse I, Grigore EI, Arruda LC, Lamartine J, Verrecchia F, Michel L.
Arthritis Res Ther. 2015 Jul 31;17:196
Screening and management of cardiovascular risk factors in systemic lupus erythematosus: Recommendations for clinical practice based on the literature and expert opinion.
Arnaud L, Mathian A, Adoue D, Bader-Meunier B, Baudouin V, Belizna C, Bonnotte B, Boumedine F, Chaib A, Chauchard M, Chiche L, Daugas E, Ghali A, Gobert P, Gondran G, Guettrot-Imbert G, Hachulla E, Hamidou M, Haroche J, Hervier B, Hummel A, Jourde-Chiche N, Korganow AS, Kwon T, Le Guern V, Le Quellec A, Limal N, Magy-Bertrand N, Marianetti-Guingel P, Martin T, Martin Silva N, Meyer O, Miyara M, Morell-Dubois S, Ninet J, Papo T, Pennaforte JL, Polomat K, Pourrat J, Queyrel V, Raymond I, Remy P, Sacre K, Schmidt J, Sibilia J, Viallard JF, Viau Brabant A, Wahl D, Bruckert E, Amoura Z; groupe France Lupus Érythémateux systémique Réseau (FLEUR) et les centres de référence et de compétence des lupus et syndromes des antiphospholipides.
Rev Med Interne. 2015 Jun;36(6):372-80. doi: 10.1016/j.revmed.2014.10.009.
2014
Cardiac assessment before stem cell transplantation for systemic sclerosis–reply.
Van Laar JM, Farge D, Tyndall A.
JAMA. 2014 Nov 5;312(17):1803-4. doi: 10.1001/jama.2014.12572.
Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis: a randomized clinical trial.
van Laar JM and Farge D, Sont JK, Naraghi K, Marjanovic Z, Larghero J, Schuerwegh AJ, Marijt EW, Vonk MC, Schattenberg AV, Matucci-Cerinic M, Voskuyl AE, van de Loosdrecht AA, Daikeler T, Kötter I, Schmalzing M, Martin T, Lioure B, Weiner SM, Kreuter A, Deligny C, Durand JM, Emery P, Machold KP, Sarrot-Reynauld F, Warnatz K, Adoue DF, Constans J, Tony HP, Del Papa N, Fassas A, Himsel A, Launay D, Lo Monaco A, Philippe P, Quéré I, Rich É, Westhovens R, Griffiths B, Saccardi R, van den Hoogen FH, Fibbe WE, Socié G, Gratwohl A, Tyndall A; EBMT/EULAR Scleroderma Study Group.
JAMA. 2014 Jun 25;311(24):2490-8. doi: 10.1001/jama.2014.6368.
Prediction of pulmonary complications and long-term survival in systemic sclerosis.
Nihtyanova SI, Schreiber BE, Ong VH, Rosenberg D, Moinzadeh P, Coghlan JG, Wells AU, Denton CP.
Arthritis Rheumatol. 2014 Jun;66(6):1625-35. doi: 10.1002/art.38390.
Autologous stem cell transplantation with thiotepa-based conditioning in patients with systemic sclerosis and cardiac manifestations.
Henes JC, Koetter I, Horger M, Schmalzing M, Mueller K, Eick C, Bauer A, Vogel W, Kanz L.
Rheumatology (Oxford). 2014 May;53(5):919-22.
Peripheral blood regulatory T cells in patients with diffuse systemic sclerosis (SSc) before and after autologous hematopoietic SCT: a pilot study.
Baraut J, Grigore EI, Jean-Louis F, Khelifa SH, Durand C, Verrecchia F, Farge D, Michel L.
Bone Marrow Transplant. 2014 Mar;49(3):349-54. doi: 10.1038/bmt.2013.202.
2013
2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative.
van den Hoogen F, Khanna D, Fransen J, Johnson SR, Baron M, Tyndall A, Matucci-Cerinic M, Naden RP, Medsger TA Jr, Carreira PE, Riemekasten G, Clements PJ, Denton CP, Distler O, Allanore Y, Furst DE, Gabrielli A, Mayes MD, van Laar JM, Seibold JR, Czirjak L, Steen VD, Inanc M, Kowal-Bielecka O, Müller-Ladner U, Valentini G, Veale DJ, Vonk MC, Walker UA, Chung L, Collier DH, Csuka ME, Fessler BJ, Guiducci S, Herrick A, Hsu VM, Jimenez S, Kahaleh B, Merkel PA, Sierakowski S, Silver RM, Simms RW, Varga J, Pope JE.
Arthritis Rheum. 2013 Nov;65(11):2737-47. doi: 10.1002/art.38098.
Autologous HSCT for systemic sclerosis – Authors’ reply.
Burt RK, Shah SJ, Schroeder J, Oliveira MC, Moraes DA, Simoes B, Marjanovic Z, Farge D.
Lancet. 2013 Jun 15;381(9883):2080-1. doi: 10.1016/S0140-6736(13)61241-6.
Functional impairment of systemic scleroderma patients with digital ulcerations: results from the DUO Registry.
Guillevin L, Hunsche E, Denton CP, Krieg T, Schwierin B, Rosenberg D, Matucci-Cerinic M; DUO Registry Group.
Clin Exp Rheumatol. 2013 Mar-Apr;31(2 Suppl 76):71-80.
Cardiac involvement and treatment-related mortality after non-myeloablative haemopoietic stem-cell transplantation with unselected autologous peripheral blood for patients with systemic sclerosis: a retrospective analysis.
Burt RK, Oliveira MC, Shah SJ, Moraes DA, Simoes B, Gheorghiade M, Schroeder J, Ruderman E, Farge D, Chai ZJ, Marjanovic Z, Jain S, Morgan A, Milanetti F, Han X, Jovanovic B, Helenowski IB, Voltarelli J.
Lancet. 2013 Mar 30;381(9872):1116-24. doi: 10.1016/S0140-6736(12)62114-X.
Autologous haematopoietic stem cell transplantation for systemic lupus erythematosus: data from the European Group for Blood and Marrow Transplantation registry.
Alchi B, Jayne D, Labopin M, Demin A, Sergeevicheva V, Alexander T, Gualandi F, Gruhn B, Ouyang J, Rzepecki P, Held G, Sampol A, Voswinkel J, Ljungman P, Fassas A, Badoglio M, Saccardi R, Farge D; EBMT Autoimmune Disease Working Party members.
Lupus. 2013 Mar;22(3):245-53. doi: 10.1177/0961203312470729.
Expression of transforming growth factor ß receptor II in mesenchymal stem cells from systemic sclerosis patients.
Vanneaux V, Farge-Bancel D, Lecourt S, Baraut J, Cras A, Jean-Louis F, Brun C, Verrecchia F, Larghero J, Michel L.
BMJ Open. 2013 Jan 7;3(1). pii: e001890. doi: 10.1136/bmjopen-2012-001890.
2012
Auto-HSCT induces sustained responses in severe systemic sclerosis patients failing pulse cyclophosphamide.
Moore J, Englert H, Furlong T, Poon T, Milliken S, Ma D.
Bone Marrow Transplant. 2012 Nov;47(11):1486-7
Juvenile and young adult-onset systemic sclerosis share the same organ involvement in adulthood: data from the EUSTAR database.
Foeldvari I, Tyndall A, Zulian F, Müller-Ladner U, Czirjak L, Denton C, Kowal-Bielecka O, Bancel DF, Matucci-Cerinic M.
Rheumatology (Oxford). 2012 Oct;51(10):1832-7
Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus.
Petri M, Orbai AM, Alarcón GS, Gordon C, Merrill JT, Fortin PR, Bruce IN, Isenberg D, Wallace DJ, Nived O, Sturfelt G, Ramsey-Goldman R, Bae SC, Hanly JG, Sánchez-Guerrero J, Clarke A, Aranow C, Manzi S, Urowitz M, Gladman D, Kalunian K, Costner M, Werth VP, Zoma A, Bernatsky S, Ruiz-Irastorza G, Khamashta MA, Jacobsen S, Buyon JP, Maddison P, Dooley MA, van Vollenhoven RF, Ginzler E, Stoll T, Peschken C, Jorizzo JL, Callen JP, Lim SS, Fessler BJ, Inanc M, Kamen DL, Rahman A, Steinsson K, Franks AG Jr, Sigler L, Hameed S, Fang H, Pham N, Brey R, Weisman MH, McGwin G Jr, Magder LS.
Arthritis Rheum. 2012 Aug;64(8):2677-86
American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis.
Hahn BH, McMahon MA, Wilkinson A, Wallace WD, Daikh DI, Fitzgerald JD, Karpouzas GA, Merrill JT, Wallace DJ, Yazdany J, Ramsey-Goldman R, Singh K, Khalighi M, Choi SI, Gogia M, Kafaja S, Kamgar M, Lau C, Martin WJ, Parikh S, Peng J, Rastogi A, Chen W, Grossman JM; American College of Rheumatology.
Arthritis Care Res (Hoboken). 2012 Jun;64(6):797-808.
Cytokines in systemic sclerosis.
Baraut J, Farge D, Jean-Louis F, Kesmandt H, Durant C, Verrecchia F, Michel L.
Pathol Biol (Paris). 2012 Apr;60(2):127-39. doi: 10.1016/j.patbio.2009.11.003.
The Systemic Lupus Erythematosus Responder Index (SRI); a new SLE disease activity assessment.
Luijten KM, Tekstra J, Bijlsma JW, Bijl M.
Autoimmun Rev. 2012 Mar;11(5):326-9.
Optimization of autologous stem cell transplantation for systemic sclerosis — a single-center longterm experience in 26 patients with severe organ manifestations.
Henes JC, Schmalzing M, Vogel W, Riemekasten G, Fend F, Kanz L, Koetter I.
J Rheumatol. 2012 Feb;39(2):269-75.
2011
Current state and future directions of autologous hematopoietic stem cell transplantation in systemic lupus erythematosus.
Illei GG, Cervera R, Burt RK, Doria A, Hiepe F, Jayne D, Pavletic S, Martin T, Marmont A, Saccardi R, Voskuyl AE, Farge D.
Ann Rheum Dis. 2011 Dec;70(12):2071-4. doi: 10.1136/ard.2010.148049.
Clinical prediction of 5-year survival in systemic sclerosis: validation of a simple prognostic model in EUSTAR centres.
Fransen J, Popa-Diaconu D, Hesselstrand R, Carreira P, Valentini G, Beretta L, Airo P, Inanc M, Ullman S, Balbir-Gurman A, Sierakowski S, Allanore Y, Czirjak L, Riccieri V, Giacomelli R, Gabrielli A, Riemekasten G, Matucci-Cerinic M, Farge D, Hunzelmann N, Van den Hoogen FH, Vonk MC.
Ann Rheum Dis. 2011 Oct;70(10):1788-92. doi: 10.1136/ard.2010.144360.
Autologous HSCT in systemic sclerosis: a step forward.
Farge D, Gluckman E.
Lancet. 2011 Aug 6;378(9790):460-2. doi: 10.1016/S0140-6736(11)61100-8.
Autologous non-myeloablative haemopoietic stem-cell transplantation compared with pulse cyclophosphamide once per month for systemic sclerosis (ASSIST): an open-label, randomised phase 2 trial.
Burt RK1, Shah SJ, Dill K, Grant T, Gheorghiade M, Schroeder J, Craig R, Hirano I, Marshall K, Ruderman E, Jovanovic B, Milanetti F, Jain S, Boyce K, Morgan A, Carr J, Barr W.
Lancet. 2011 Aug 6;378(9790):498-506. doi: 10.1016/S0140-6736(11)60982-3.
2010
Relationship between cytokine profiles and clinical outcomes in patients with systemic sclerosis.
Baraut J, Michel L, Verrecchia F, Farge D.
Autoimmun Rev. 2010 Dec;10(2):65-73. doi: 10.1016/j.autrev.2010.08.003.
Prevalence of pulmonary hypertension in systemic sclerosis in European Caucasians and metaanalysis of 5 studies.
Avouac J, Airò P, Meune C, Beretta L, Dieude P, Caramaschi P, Tiev K, Cappelli S, Diot E, Vacca A, Cracowski JL, Sibilia J, Kahan A, Matucci-Cerinic M, Allanore Y.
J Rheumatol. 2010 Nov;37(11):2290-8. doi: 10.3899/jrheum.100245.
Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database.
Tyndall AJ, Bannert B, Vonk M, Airò P, Cozzi F, Carreira PE, Bancel DF, Allanore Y, Müller-Ladner U, Distler O, Iannone F, Pellerito R, Pileckyte M, Miniati I, Ananieva L, Gurman AB, Damjanov N, Mueller A, Valentini G, Riemekasten G, Tikly M, Hummers L, Henriques MJ, Caramaschi P, Scheja A, Rozman B, Ton E, Kumánovics G, Coleiro B, Feierl E, Szucs G, Von Mühlen CA, Riccieri V, Novak S, Chizzolini C, Kotulska A, Denton C, Coelho PC, Kötter I, Simsek I, de la Pena Lefebvre PG, Hachulla E, Seibold JR, Rednic S, Stork J, Morovic-Vergles J, Walker UA.
Ann Rheum Dis. 2010 Oct;69(10):1809-15. doi: 10.1136/ard.2009.114264.
Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma.
Hill GR, Olver SD, Kuns RD, Varelias A, Raffelt NC, Don AL, Markey KA, Wilson YA, Smyth MJ, Iwakura Y, Tocker J, Clouston AD, Macdonald KP.
Blood. 2010 Aug 5;116(5):819-28
Disease activity and damage accrual during the early disease course in a multinational inception cohort of patients with systemic lupus erythematosus.
Nossent J, Kiss E, Rozman B, Pokorny G, Vlachoyiannopoulos P, Olesinska M, Marchesoni A, Mosca M, Påi S, Manger K, Schneider M, Nielsen H, van Vollenhoven R, Swaak T.
Lupus. 2010 Jul;19(8):949-56.
Peripheral B cell abnormalities in patients with systemic lupus erythematosus in quiescent phase: decreased memory B cells and membrane CD19 expression.
Korganow AS, Knapp AM, Nehme-Schuster H, Soulas-Sprauel P, Poindron V, Pasquali JL, Martin T.
J Autoimmun. 2010 Jun;34(4):426-34. doi: 10.1016/j.jaut.2009.11.002.
Prevalence and factors associated with left ventricular dysfunction in the EULAR Scleroderma Trial and Research group (EUSTAR) database of patients with systemic sclerosis.
Allanore Y, Meune C, Vonk MC, Airo P, Hachulla E, Caramaschi P, Riemekasten G, Cozzi F, Beretta L, Derk CT, Komócsi A, Farge D, Balbir A, Riccieri V, Distler O, Chialà A, Del Papa N, Simic KP, Ghio M, Stamenkovic B, Rednic S, Host N, Pellerito R, Zegers E, Kahan A, Walker UA, Matucci-Cerinic M; EUSTAR co-authors.
Ann Rheum Dis. 2010 Jan;69(1):218-21. doi: 10.1136/ard.2008.103382.
2009
Autologous hematopoietic stem cell transplant in systemic sclerosis: quantitative high resolution computed tomography of the chest scoring.
Launay D, Marjanovic Z, de Bazelaire C, Florea L, Zohar S, Keshtmand H, Deligny C, de Raigniac A, Wells AU, Farge D.
J Rheumatol. 2009 Jul;36(7):1460-3. doi: 10.3899/jrheum.081212.
The three-year incidence of pulmonary arterial hypertension associated with systemic sclerosis in a multicenter nationwide longitudinal study in France.
Hachulla E, de Groote P, Gressin V, Sibilia J, Diot E, Carpentier P, Mouthon L, Hatron PY, Jego P, Allanore Y, Tiev KP, Agard C, Cosnes A, Cirstea D, Constans J, Farge D, Viallard JF, Harle JR, Patat F, Imbert B, Kahan A, Cabane J, Clerson P, Guillevin L, Humbert M; Itinér AIR-Sclérodermie Study Group.
Arthritis Rheum. 2009 Jun;60(6):1831-9. doi: 10.1002/art.24525
Geographical variation of disease manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials and Research (EUSTAR) group database.
Walker UA, Tyndall A, Czirják L, Denton CP, Farge-Bancel D, Kowal-Bielecka O, Müller-Ladner U, Matucci-Cerinic M; EUSTAR co-authors.
Ann Rheum Dis. 2009 Jun;68(6):856-62. doi: 10.1136/ard.2008.091348.
European League Against Rheumatism (EULAR) Scleroderma Trial and Research group (EUSTAR) recommendations for the treatment of systemic sclerosis: methods of elaboration and results of systematic literature research.
Avouac J, Kowal-Bielecka O, Landewe R, Chwiesko S, Miniati I, Czirjak L, Clements P, Denton C, Farge D, Fligelstone K, Földvari I, Furst DE, Müller-Ladner U, Seibold J, Silver RM, Takehara K, Toth BG, Tyndall A, Valentini G, van den Hoogen F, Wigley F, Zulian F, Matucci-Cerinic M; EUSTAR Coauthors.
Ann Rheum Dis. 2009 May;68(5):629-34. doi: 10.1136/ard.2008.095299.
EULAR recommendations for the treatment of systemic sclerosis: a report from the EULAR Scleroderma Trials and Research group (EUSTAR).
Kowal-Bielecka O, Landewé R, Avouac J, Chwiesko S, Miniati I, Czirjak L, Clements P, Denton C, Farge D, Fligelstone K, Földvari I, Furst DE, Müller-Ladner U, Seibold J, Silver RM, Takehara K, Toth BG, Tyndall A, Valentini G, van den Hoogen F, Wigley F, Zulian F, Matucci-Cerinic M; EUSTAR Co-Authors.
Ann Rheum Dis. 2009 May;68(5):620-8. doi: 10.1136/ard.2008.096677.
2008
Autologous stem cell transplantation for systemic sclerosis.
Farge D, Nash R, Laar JM.
Autoimmunity. 2008 Dec;41(8):616-24. doi: 10.1080/08916930802197305.
Stem cell transplantation: a treatment option for severe systemic sclerosis?
Van Laar JM, Farge D, Tyndall A.
Ann Rheum Dis. 2008 Dec;67 Suppl 3:iii35-8. doi: 10.1136/ard.2008.098384.
Pregnancy and childbirth after treatment with autologous hematopoietic stem cell transplantation for severe systemic sclerosis requiring parenteral nutrition. Ethical issues.
Tyndall AJ, Joly F, Carbonne B, Deligny CN, Farge DC.
Clin Exp Rheumatol. 2008 Nov-Dec;26(6):1122-4.
Phenotypical and functional characteristics of in vitro expanded bone marrow mesenchymal stem cells from patients with systemic sclerosis.
Larghero J, Farge D, Braccini A, Lecourt S, Scherberich A, Foïs E, Verrecchia F, Daikeler T, Gluckman E, Tyndall A, Bocelli-Tyndall C.
Ann Rheum Dis. 2008 Apr;67(4):443-9.
Long-term follow-up results after autologous haematopoietic stem cell transplantation for severe systemic sclerosis.
Vonk MC1, Marjanovic Z, van den Hoogen FH, Zohar S, Schattenberg AV, Fibbe WE, Larghero J, Gluckman E, Preijers FW, van Dijk AP, Bax JJ, Roblot P, van Riel PL, van Laar JM, Farge D.
Ann Rheum Dis. 2008 Jan;67(1):98-104.
2007
High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for severe systemic sclerosis: long-term follow-up of the US multicenter pilot study.
Nash RA, McSweeney PA, Crofford LJ, Abidi M, Chen CS, Godwin JD, Gooley TA, Holmberg L, Henstorf G, LeMaistre CF, Mayes MD, McDonagh KT, McLaughlin B, Molitor JA, Nelson JL, Shulman H, Storb R, Viganego F, Wener MH, Seibold JR, Sullivan KM, Furst DE.
Blood. 2007 Aug 15;110(4):1388-96
Skin involvement in scleroderma–where histological and clinical scores meet.
Verrecchia F, Laboureau J, Verola O, Roos N, Porcher R, Bruneval P, Ertault M, Tiev K, Michel L, Mauviel A, Farge D.
Rheumatology (Oxford). 2007 May;46(5):833-41.
In vitro evidence for a direct antifibrotic role of the immunosuppressive drug mycophenolate mofetil.
Roos N, Poulalhon N, Farge D, Madelaine I, Mauviel A, Verrecchia F
J Pharmacol Exp Ther. 2007 May;321(2):583-9
2006
Modulation of collagen and MMP-1 gene expression in fibroblasts by the immunosuppressive drug rapamycin. A direct role as an antifibrotic agent?
Poulalhon N, Farge D, Roos N, Tacheau C, Neuzillet C, Michel L, Mauviel A, Verrecchia F
J Biol Chem. 2006 Nov 3;281(44):33045-52. Epub 2006 Aug 16.
Impact of pain in health related quality of life of patients with systemic sclerosis.
Georges C, Chassany O, Toledano C, Mouthon L, Tiev K, Meyer O, Ilie D, Rambeloarisoa J, Marjanovic Z, Cabane J, Sereni D, Pouchot J, Farge D.
Rheumatology (Oxford). 2006 Oct;45(10):1298-302. Epub 2006 Jun 4.
Transforming growth factor-beta signaling through the Smad proteins: role in systemic sclerosis.
Verrecchia F, Mauviel A, Farge D
Autoimmun Rev. 2006 Oct;5(8):563-9. Epub 2006 Jul 5
MR evaluation of the glomerular homing of magnetically labeled mesenchymal stem cells in a rat model of nephropathy.
Hauger O, Frost EE, van Heeswijk R, Deminière C, Xue R, Delmas Y, Combe C, Moonen CT, Grenier N, Bulte JW.
Radiology. 2006 Jan;238(1):200-10.
2005
Combined oral contraceptives in women with systemic lupus erythematosus.
Petri M, Kim MY, Kalunian KC, Grossman J, Hahn BH, Sammaritano LR, Lockshin M, Merrill JT, Belmont HM, Askanase AD, McCune WJ, Hearth-Holmes M, Dooley MA, Von Feldt J, Friedman A, Tan M, Davis J, Cronin M, Diamond B, Mackay M, Sigler L, Fillius M, Rupel A, Licciardi F, Buyon JP; OC-SELENA Trial.
N Engl J Med. 2005 Dec 15;353(24):2550-8
Autologous Stem cell Transplantation International Scleroderma (ASTIS) trial: hope on the horizon for patients with severe systemic sclerosis.
Van Laar JM, Farge D, Tyndall A.
Ann Rheum Dis. 2005 Oct;64(10):1515.
BILAG 2004. Development and initial validation of an updated version of the British Isles Lupus Assessment Group’s disease activity index for patients with systemic lupus erythematosus.
Isenberg DA, Rahman A, Allen E, Farewell V, Akil M, Bruce IN, D’Cruz D, Griffiths B, Khamashta M, Maddison P, McHugh N, Snaith M, Teh LS, Yee CS, Zoma A, Gordon C.
Rheumatology (Oxford). 2005 Jul;44(7):902-6
[Cardiopulmonary function before and after cyclophosphamide treatment in severe systemic sclerosis: comparison of monthly intravenous bolus and autologous haematopoietic stem cell transplantation].
Toledano C, Henegar C, Ilie D, Launay D, Tiev K, Marie I, Marjanovic Z, Emmerich J, Cabane J, Ménasché S, Farge D.
Rev Med Interne. 2005 Jun;26(6):444-52
Analysis of immune reconstitution after autologous bone marrow transplantation in systemic sclerosis.
Farge D, Henegar C, Carmagnat M, Daneshpouy M, Marjanovic Z, Rabian C, Ilie D, Douay C, Mounier N, Clave E, Bengoufa D, Cabane J, Marolleau JP, Gluckman E, Charron D, Toubert A.
Arthritis Rheum. 2005 May;52(5):1555-63.
Validation of French version of the Scleroderma Health Assessment Questionnaire (SSc HAQ).
Georges C, Chassany O, Mouthon L, Tiev K, Toledano C, Meyer O, Marjanovic Z, Heneggar C, Papo T, Crickx B, Sereni D, Cabane J, Farge D.
Clin Rheumatol. 2005 Feb;24(1):3-10.
2004
Consensus statement concerning cardiotoxicity occurring during haematopoietic stem cell transplantation in the treatment of autoimmune diseases, with special reference to systemic sclerosis and multiple sclerosis.
Saccardi R, Tyndall A, Coghlan P, Denton C, Edan G, Emdin M, Farge D et al.
Bone Marrow Transplant. 2004 Nov;34(10):877-81.
Autologous stem cell transplantation in the treatment of systemic sclerosis: report from the EBMT/EULAR Registry.
Farge D, Passweg J, van Laar JM, Marjanovic Z, Besenthal C, Finke J, Peter HH, Breedveld FC, Fibbe WE, Black C, Denton C, Koetter I, Locatelli F, Martini A, Schattenberg AV, van den Hoogen F, van de Putte L, Lanza F, Arnold R, Bacon PA, Bingham S, Ciceri F, Didier B, Diez-Martin JL, Emery P, Feremans W, Hertenstein B, Hiepe F, Luosujärvi R, Leon Lara A, Marmont A, Martinez AM, Pascual Cascon H, Bocelli-Tyndall C, Gluckman E, Gratwohl A, Tyndall A; EBMT/EULAR Registry.
Ann Rheum Dis. 2004 Aug;63(8):974-81.
Autologous stem cell transplantation for systemic lupus erythematosus.
Jayne D, Passweg J, Marmont A, Farge D, Zhao X, Arnold R, Hiepe F, Lisukov I, Musso M, Ou-Yang J, Marsh J, Wulffraat N, Besalduch J, Bingham SJ, Emery P, Brune M, Fassas A, Faulkner L, Ferster A, Fiehn C, Fouillard L, Geromin A, Greinix H, Rabusin M, Saccardi R, Schneider P, Zintl F, Gratwohl A, Tyndall A; European Group for Blood and Marrow Transplantation; European League Against Rheumatism Registry.
Lupus. 2004;13(3):168-76.
2002
Autologous bone marrow transplantation in the treatment of refractory systemic sclerosis: early results from a French multicentre phase I-II study.
Farge D, Marolleau JP, Zohar S, Marjanovic Z, Cabane J, Mounier N, Hachulla E, Philippe P, Sibilia J, Rabian C, Chevret S, Gluckman E; Intensification et Autogreffe dans les Maladies Auto Immunes Resistantes (ISAMAIR) Study Group.
Br J Haematol. 2002 Dec;119(3):726-39.
2001
Phase I/II trial of autologous stem cell transplantation in systemic sclerosis: procedure related mortality and impact on skin disease.
Binks M, Passweg JR, Furst D, McSweeney P, Sullivan K, Besenthal C, Finke J, Peter HH, van Laar J, Breedveld FC, Fibbe WE, Farge D, Gluckman E, Locatelli F, Martini A, van den Hoogen F, van de Putte L, Schattenberg AV, Arnold R, Bacon PA, Emery P, Espigado I, Hertenstein B, Hiepe F, Kashyap A, Kötter I, Marmont A, Martinez A, Pascual MJ, Gratwohl A, Prentice HG, Black C, Tyndall A.
Ann Rheum Dis, 2001 Jun;60(6):577-84.
[Quality of life assessment with the MOS-SF36 in patients with systemic sclerosis].
Georges C, Chassany O, Mouthon L, Tiev K, Marjanovic Z, Meyer O, Toledano C, Ilie D, Guillevin L, Sereni D, Cabane J, Farge D.
Rev Med Interne. 2004 Jan;25(1):16-21