Maladie de Crohn


Les références en gras ont été publiées par les membres de MATHEC

Les références en italique ont pour sujet les cellules stromales mésenchymateuses

2023


Misconceptions, hurdles and recommendations regarding the use of mesenchymal stem/stromal cells in perianal Crohn disease

Ciccocioppo R, Guadalajara H, Astori G, Carlino G, García-Olmo D
Cytotherapy Volume 25, Issue 3, March 2023, Pages 230-234. https://doi.org/10.1016/j.jcyt.2022.11.011


Deep remission improves the quality of life of patients with Crohn’s disease and anoperineal fistula treated with darvadstrocel: results of a French pilot study

Fathallah N, Akaffou M, Haouari M. A, Spindler L , Alam A, Barré A, Pommaret E, Fels A, De Parades V.
Tech Coloproctol. 2023 Feb 22. doi: 10.1007/s10151-023-02765-7.

2022


Adult allogenic bone marrow-derived mesenchymal stem cells for the treatment of rectovaginal fistulas in the setting of Crohn’s disease

Otero-Piñeiro AM, Lightner AL
Tech Coloproctol. 2022 Aug 1.doi: 10.1007/s10151-022-02667-0.


Mesenchymal Stem/Stromal Cell Therapy Is More Cost-Effective Than Fecal Diversion for Treatment of Perianal Crohn’s Disease Fistulas

Johnson S, Hoch JS, Halabi WJ, Ko J, Nolta J, Dave M
Front Immunol. 2022 Jun 17;13:859954.doi: 10.3389/fimmu.2022.859954. eCollection 2022.


Remestemcel-L allogeneic bone marrow-derived mesenchymal stem cell product to treat medically refractory Crohn’s colitis: preliminary phase IB/IIA study

Lightner AL, Ream J, Nachand D, Fulmer C, Regueiro M, Steele SR
Br J Surg. 2022 Jul 15;109(8):653-655.doi: 10.1093/bjs/znac078.

2021

Intestinal Microbiome in Hematopoietic Stem Cell Transplantation For Autoimmune Diseases: Considerations and Perspectives on Behalf of Autoimmune Diseases Working Party (ADWP) of the EBMT
Alexander T, Snowden J A, Burman J, Chang H-D, Del Papa N, Farge D, Lindsay J O, Malard F, Muraro P A, Nitti R, Salas A, Sharrack B, Mohty M, Greco R
Front Oncol. 2021 Oct 22;11:722436.doi: 10.3389/fonc.2021.722436. eCollection 2021.


Follow-up Study to Evaluate the Long-term Safety and Efficacy of Darvadstrocel (Mesenchymal Stem Cell Treatment) in Patients with Perianal Fistulizing Crohn’s Disease: ADMIRE-CD Phase 3 Randomized Controlled Trial

Garcia-Olmo D, Gilaberte I, Binek M, Jl D Hoore A, Lindner D, Selvaggi F, Spinelli A, Panés J
Dis Colon Rectum. 2021 Dec 7.doi: 10.1097/DCR.0000000000002325. Online ahead of print.

2020

Inflammatory bowel disease: Therapeutic limitations and prospective of the stem cell therapy
Mishra R, Dhawan P, Srivastava AS, Singh AB
World J Stem Cells. 2020 Oct 26;12(10):1050-1066. doi: 10.4252/wjsc.v12.i10.1050.

[Crohn’s disease and autologous hemapoietic cell transplantation: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)]
[Article in French]
Puyade M, Treton X, Alric L, Badoglio M, Castilla Llorente C, Fotsing G, Marjanovic Z, Rovira M, Terriou L, Torregrosa Díaz Jose M, Tran-Minh M-L, Allez M, Pugnet G, Laharie D, Yakoub-Agha I, Farge D
Bull Cancer. 2020 Oct 13;S0007-4551(20)30372-6. doi: 10.1016/j.bulcan.2020.08.009.


A pilot feasibility study of non-myeloablative allogeneic hematopoietic stem cell transplantation for refractory Crohn Disease
Burt RK, Craig R, Yun L, Halverson A, Quigley K, Arnautovic I, Han X
Bone Marrow Transplant. 2020 May 28. doi: 10.1038/s41409-020-0953-y.

2019

Perspectives of the International Society for Cell & Gene Therapy Gastrointestinal Scientific Committee on the Intravenous Use of Mesenchymal Stromal Cells in Inflammatory Bowel Disease (PeMeGi)
Ciccocioppo R, Baumgart DC, Dos Santos CC, Galipeau J, Klersy C, Orlando G
Cytotherapy. 2019 Aug;21(8):824-839.doi: 10.1016/j.jcyt.2019.05.003. Epub 2019 Jun 11.

Mesenchymal Stem Cells for Perianal Crohn’s Disease
Carvello M, Lightner A, Yamamoto T, Kotze PG, Spinelli A
Cells. 2019 Jul 23;8(7). pii: E764. doi: 10.3390/cells8070764.

Autologous stem cell transplantation in refractory Crohn’s disease – low intensity therapy evaluation (ASTIClite): study protocols for a multicentre, randomised controlled trial and observational follow up study.
Snowden JA, Hawkey C, Hind D, Swaby L, Mellor K, Emsley R, Mandefield L, Lee E, Badoglio M, Polge E, Labopin M, Gribben J, Pockley AG, Foulds GA, Lobo A, Travis S, Parkes M, Satsangi J, Papaioannou D, Lindsay JO; Autologous Stem Cell Transplantation In Refractory CD – Low Intensity Therapy Evaluation Study Investigators; European Society for Blood and Marrow Transplantation (EBMT) Autoimmune Diseases Working Party (ADWP).
BMC Gastroenterol. 2019 May 31;19(1):82. doi: 10.1186/s12876-019-0992-2.

2018

Long-term Efficacy and Safety of Stem Cell Therapy (Cx601) for Complex Perianal Fistulas in Patients With Crohn’s Disease
Panés J, García-Olmo D, Van Assche G, Colombel JF, Reinisch W, Baumgart DC Dignass A, Nachury M, Ferrante M, Kazemi-Shirazi L, Grimaud JC, de la Portilla F, Goldin E, Richard MP, Diez MC, Tagarro I, Leselbaum A, Danese S, ADMIRE CD Study Group Collaborators
Gastroenterology. 2018 Apr;154(5):1334-1342.e4.doi: 10.1053/j.gastro.2017.12.020. Epub 2017 Dec 24.

A Systematic Review and Meta-analysis of Mesenchymal Stem Cell Injections for the Treatment of Perianal Crohn’s Disease: Progress Made and Future Directions.
Lightner AL, Wang Z, Zubair AC, Dozois EJ.
Dis Colon Rectum. 2018 May;61(5):629-640. doi: 10.1097/DCR.0000000000001093.

Autologous Haematopoietic Stem Cell Transplantation for Crohn’s Disease: A Retrospective Survey of Long-term Outcomes from the European Society for Blood and Marrow Transplantation.
Brierley CK, Castilla-Llorente C, Labopin M, Badoglio M, Rovira M, Ricart E, Dierickx D, Vermeire S, Hasselblatt P, Finke J, Onida F, Cassinotti A, Satsangi J, Kazmi M, López-Sanromán A, Schmidt C, Farge D, Travis SPL, Hawkey CJ, Snowden JA; European Society for Blood and Marrow Transplantation (EBMT) Autoimmune Diseases Working Party (ADWP).
J Crohns Colitis. 2018 May 18.

Immune Reconstitution After Autologous Hematopoietic Stem Cell Transplantation in Crohn’s Disease: Current Status and Future Directions. A Review on Behalf of the EBMT Autoimmune Diseases Working Party and the Autologous Stem Cell Transplantation In Refractory CD-Low Intensity Therapy Evaluation Study Investigators.
Pockley AG, Lindsay JO, Foulds GA, Rutella S, Gribben JG, Alexander T, Snowden JA.
Front Immunol. 2018 Apr 4;9:646

2017

3rd European Evidence-based Consensus on the Diagnosis and Management of Crohn’s Disease 2016: Part 1: Diagnosis and Medical Management
Gomollón F, Dignass A, Annese V, Tilg H, Van Assche G, Lindsay JO, Peyrin-Biroulet L, Cullen GJ, Daperno M, Kucharzik T, Rieder F, Almer S, Armuzzi A, Harbord M, Langhorst J, Sans M, Chowers Y, Fiorino G, Juillerat p, Mantzaris GJ, Rizzello F, Vavricka S, Gionchetti P, on behalf of ECCO
J Crohns Colitis. 2017 Jan;11(1):3-25. doi: 10.1093/ecco-jcc/jjw168. Epub 2016 Sep 22.

Autologous stem-cell transplantation in treatment-refractory Crohn’s disease: an analysis of pooled data from the ASTIC trial.
Lindsay JO, Allez M, Clark M, Labopin M, Ricart E, Rogler G, Rovira M, Satsangi J, Farge D, Hawkey CJ; ASTIC trial group; European Society for Blood and Marrow Transplantation Autoimmune Disease Working Party; European Crohn’s and Colitis Organisation.
Lancet Gastroenterol Hepatol. 2017 Jun;2(6):399-406.

Hematopoietic stem cell transplantation in a severe refractory Crohn’s disease patient with intestinal stoma: a case report.
Ruiz MA, Kaiser Junior RL, de Quadros LG, Caseiro GHX, Oliveira AF, Peña-Arciniegas T, Piron-Ruiz L, Kaiser FSL, Oliveira VL.
Int Med Case Rep J. 2017 Oct 24;10:353-359.

Autologous hematopoietic stem cells for refractory Crohn’s disease.
DiNicola CA, Zand A, Hommes DW.
Expert Opin Biol Ther. 2017 May;17(5):555-564.

Resetting of the Mucosal T Cell Repertoire after Hematopoietic Stem Cell Transplantation in Refractory Crohn’s Disease.
Lionel Le Bourhis, Ana Maria Corraliza, Claire Auzolle, Elena Ricart, Christopher J. Hawkey, James O. Lindsay, Miranda M. Clark, Gerhard Rogler, Jack Satsangi, Dirk Haller, Julian Panes, Azucena Salas, Matthieu Allez.
Gastroenterol. 2017 Apr; 152(5): S613–S614.

2016

Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn’s disease: a phase 3 randomised, double-blind controlled trial
Panés J, García-Olmo D, Van Assche G, Colombel JF, Reinisch W, Baumgart DC, Dignass A, Nachury M, Ferrante M, Kazemi-Shirazi L, Grimaud JC, de la Portilla F, Goldin E, Richard MP, Leselbaum A, Danese S, ADMIRE CD Study Group Collaborators
Lancet. 2016 Sep 24;388(10051):1281-90.doi: 10.1016/S0140-6736(16)31203-X. Epub 2016 Jul 29.

Improving safety of autologous haematopoietic stem cell transplantation in patients with Crohn’s disease.
Jauregui-Amezaga A, Rovira M, Marín P, Salas A, Pinó-Donnay S, Feu F, Elizalde JI, Fernández-Avilés F, Martínez C, Gutiérrez G, Rosiñol L, Carreras E, Urbano A, Lozano M, Cid J, Suárez-Lledó M, Mensa J, Rimola J, Rodríguez S, Masamunt MC, Comas D, Ruíz I, Ramírez-Morros A, Gallego M, Ordás I, Panés J, Ricart E.
Gut. 2016 Sep;65(9):1456-62. doi: 10.1136/gutjnl-2015-309836.

Stem Cell Transplantation for Refractory Crohn Disease.
Burt RK, Ruiz MA, Kaiser RL Jr.
JAMA. 2016 Jun 21;315(23):2620. doi: 10.1001/jama.2016.4030.

2015

Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial.
Hawkey CJ, Allez M, Clark MM, Labopin M, Lindsay JO, Ricart E, Rogler G, Rovira M, Satsangi J, Danese S, Russell N, Gribben J, Johnson P, Larghero J, Thieblemont C, Ardizzone S, Dierickx D, Ibatici A, Littlewood T, Onida F, Schanz U, Vermeire S, Colombel JF, Jouet JP, Clark E, Saccardi R, Tyndall A, Travis S, Farge D.
JAMA. 2015 Dec 15;314(23):2524-34. doi: 10.1001/jama.2015.16700.